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Multimodal identification of white-matter pathways - Aviv Mezer

October 11, 2019 - 9:30am
Jordan Hall, Room 419

Aviv Mezer


Edmond and Lily Safra Center for Brain Sciences, Hebrew University


Diffusion MRI tractography algorithms are essential for reconstructing major, long-range, white-matter projections in the living human brain. However, there are still considerable challenges in achieving meaningful usage of these algorithms. In particular, the crossing and mixture of white-matter fibers add ambiguity to the estimation of the local fiber orientation from the diffusion MRI signal. Hence, the white-matter reconstructions from different tractography algorithms depend on the underlying assumptions made to overcome this ambiguity. It has been argued that only by integrating additional, non-diffusion structural information can the current limiting uncertainty be solved. I will show how such an integrative approach can be extended to identify pathways such as the vertical occipital fasciculus (VOF) and the superior longitudinal fasciculus (SLF). Additionally, I will discuss the reliability of asymmetry estimations of the arcuate fasciculus, another white-matter pathway, and the adjacent cortical regions, using multiple-dataset and quantitative approaches

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Vision Brunch (Psychology Department)
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