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Advancing Our Understanding of the Brain Epitranscriptome (R21) (PAR-17-152)

National Institutes of Health
Funding Sponsor: 
National Institutes of Health
Contact Email: 
GrantsInfo@nih.gov
Funding Deadline: 
February 16, 2018 - 11:59 pm

Advancing Our Understanding of the Brain Epitranscriptome (R21) (PAR-17-152)

National Institute of Mental Health

R21-exploratory developmental award mechanism  

Background: Chemical modifications of proteins, DNA and RNA nucleoside moieties play a crucial role on gene regulation. The role of chemical modifications of RNA molecules (the epitranscriptome) in mediating brain functions is relatively unexplored.  A few covalent RNA modifications have been studied extensively, and recent evidence suggests that other newly discovered RNA modifications have interesting biological and disease functions in mammals. 

Standard R21 exploratory/developmental award deadlines:  Feb. 16, June 16, Oct. 16

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