Research topics: We aim to identify new disease targets and develop novel RNA-based therapeutics.
Techniques: We use single-cell technologies, human genetics, patient tissues, and mouse models.
Seeking undergrads for: Academic year
Location: Flexible, with possibilities for remote or on-campus research projects
Required skills: Previous wet lab experience
This lab is particularly interested in mentoring: Undergrads from backgrounds that are underrepresented in STEM
How to apply: Contact Sean Wang (email@example.com)
Project information: 1) Circular RNAs are a type of RNA molecule resistant to degradation and may be promising for gene therapy. This project will optimize the in vivo properties of circular RNAs with the goal of creating a new class of therapeutics for genetic diseases.
2) The majority of genetic variants associated with disease occur in noncoding regions of the genome. This project will use single-cell genomics and epigenomics specifically on human eye tissues to help uncover how these noncoding variants contribute to conditions such as glaucoma, macular degeneration, and myopia.