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Chang Lab: academic year and summer opportunities

Howard Chang
Funding Sponsor: 
Dr. Howard Chang
Contact Email: 
Sean Wang (
Funding Deadline: 
May 30, 2022 - 11:59 pm

Research topics: We aim to identify new disease targets and develop novel RNA-based therapeutics.

Techniques: We use single-cell technologies, human genetics, patient tissues, and mouse models.

Seeking undergrads for: Academic year

Location: Flexible, with possibilities for remote or on-campus research projects

Required skills: Previous wet lab experience

This lab is particularly interested in mentoring: Undergrads from backgrounds that are underrepresented in STEM

How to apply: Contact Sean Wang (

Project information: 1) Circular RNAs are a type of RNA molecule resistant to degradation and may be promising for gene therapy. This project will optimize the in vivo properties of circular RNAs with the goal of creating a new class of therapeutics for genetic diseases.

2) The majority of genetic variants associated with disease occur in noncoding regions of the genome. This project will use single-cell genomics and epigenomics specifically on human eye tissues to help uncover how these noncoding variants contribute to conditions such as glaucoma, macular degeneration, and myopia.