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Knight Initiative | News

Aug 24 2023 Knight Initiative for Brain Resilience
Pathologist Siddhartha Jaiswal discovers a surprising twist to our biology: age-related mutations that increase the risk of blood disease also protect against brain disease.
Aug 21 2023 GEN
A study in mice suggests that the most pronounced changes that occur over time are in the white matter—neurons that are integral to transmitting signals across the brain. The research also examined how two anti-aging treatments—caloric restriction and infusions of plasma from young mice—affect...
Aug 21 2023 Neuroscience News

Researchers at the Wyss-Coray Lab have discovered that age-related cognitive decline is most pronounced in the brain’s white matter in a new study funded in part by the Knight Initiative for Brain Resilience.

Aug 17 2023 Stanford Medicine
A study in mice finds that white matter — the tissue that transmits messages around the brain — shows the greatest changes as the animals age.
May 16 2023 Wu Tsai Neuro
A new study demonstrating CRISPR gene editing in killifish opens the doors for ambitious research on the biological drivers of aging.
Jan 27 2023 Wu Tsai Neurosciences Institute
Interdisciplinary Postdocs and Brain Resilience Scholars will advance knowledge of brain health and aging.
Dec 19 2022 Wu Tsai Neuro

New insights into the drivers of aging are emerging from research using an automated system for care and monitoring of hundreds of short-lived fish developed in the Wu Tsai Neuroscience Institute’s Sandbox Laboratory.

Dec 8 2022 Knight Initiative for Brain Resilience
The Knight Initiative for Brain Resilience is proud to announce the recipients of its inaugural 2022 Innovation and Catalyst Grants. These 16 groundbreaking research projects will receive a total of $15.5 million to pursue fresh ideas in the science of healthy brain aging and spearhead innovative...
Nov 15 2022 Knight Initiative for Brain Resilience
Knight Initiative researchers report that identified novel molecular markers capable of tracking the progression of Parkinson’s disease. Biomarkers for Parkinson’s are currently in short supply and are urgently needed to guide clinical care, support earlier diagnosis, and hasten drug development.
Jul 29 2022 Scope Blog
Tony Wyss-Coray and colleagues have turned up substances in blood that can accelerate or slow down the brain-aging clock. They've identified proteins on blood-vessel surfaces through which some of these molecules can act on the brain, despite the existence of the blood-brain barrier.


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