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Funded Research Projects

NeuroDiscovery | Postdoctoral Fellowship
Lead Researcher(s): Corianne van den Akker
Ion channels in the membranes of neuronal cells are the key regulators of neuronal signaling. An ion channel works as a gate that can open and close to allow specific molecules to enter or leave the cell. One important type of ion channels are voltage-gated sodium channels (NaVs), which are...
NeuroDiscovery | Postdoctoral Fellowship
Lead Researcher(s): Mariapaola Sidoli
Cyclic adenosine monophosphate (cAMP) is an important intracellular messenger that plays a critical role in the development of the central and peripheral nervous system. However, the mechanisms of action of cAMP in the nervous system development are poorly understood and there are currently no...
NeuroDiscovery | Postdoctoral Fellowship
Lead Researcher(s): Hongjie Li
Precise neural circuit assembly is critical for appropriate function of the nervous system. A functional circuit requires proper targeting and matching of axons and dendrites of pre- and post-synaptic neurons. However, our understanding of the mechanisms that establish wiring specificity of complex...
NeuroDiscovery | Postdoctoral Fellowship
Lead Researcher(s): Kyle Brewer
One in three people will develop Alzheimer’s disease or another dementia during their lifetime, but effective treatment still does not exist despite intense efforts. Recently, blood from young mice has been found to rejuvenate several tissues of old mice, including the brain. By using transfusions...
NeuroDiscovery | EPFL-Stanford Exchange
Lead Researcher(s): Luis de Lecea
The purpose of this collaborative project is to study neuronal mechanisms associated with social stress. In particular we will test whether the energy producing systems, known as mitochondria, in a specific set of brain cells are important to confer resilience to stressful stimuli. This research...
Lead Researcher(s): Xiaoke Chen
To understand how sensory information and physiological state integrate to drive decisions and behaviors. Dr. Xiaoke Chen's lab is focusing now on interoception, which is the sense of the physiological condition of the body. This include our abilities to feel hungry or satiated, to sense heightened...
NeuroDiscovery | Postdoctoral Fellowship
Lead Researcher(s): Andrew Whittle
Everyone is well aware of their white adipose tissue and its ability to store excess energy as fat. In fact the efficiency with which it does this has led to obesity and related metabolic diseases becoming the largest single health burden in the United States. Yet buried behind our collar-bones and...
NeuroDiscovery | SIGF - Graduate Fellowship
Lead Researcher(s): Kiah Hardcastle
Navigation through an environment to a remembered location is a critical skill we use every day. How does our brain accomplish such a task? Over the last few decades, several lines of evidence have suggested that a brain region called medial entorhinal cortex (MEC) supports navigation by encoding...
NeuroDiscovery | SIGF - Graduate Fellowship
Lead Researcher(s): Kevin Guttenplan
Many neurological diseases feature the death of neurons, but the mechanisms that mediate cell death in these disorders are unknown. Astrogliosis, the response of a cell-type called “astrocytes” to injury, is common to most diseases of the central nervous system (CNS), and recent studies in our lab...
NeuroDiscovery | Seed Grant
We aim to understand how brain mechanisms of spatial reasoning are brought into play during symbolic mathematical cognition and to identify individual differences in these mechanisms that co-vary with mathematical ability and mathematical experience.