Funded Research Projects
NeuroEngineering | Neuroscience:Translate
Recurrent dizziness attacks are a debilitating condition for 10% of the population during their lifetime, and can lead to a complete inability to function, and to multiple hospital admissions and investigations chasing many potential diagnoses. This project aims to address the unmet need for means...
NeuroEngineering | Postdoctoral Fellowship
Lead Researcher(s): Rui Lin
Multicellular organisms consist of numerous cell types with specialized biological functions. To understand such complex biological systems, genetic access to each cell type is needed for functional analysis and manipulations. Most current cell-type targeting strategies rely on germline...
NeuroHealth | Postdoctoral Fellowship
Lead Researcher(s): Mable Lam
Myelin is the protective covering that surrounds nerve fibers to accelerate communication between different parts of the nervous system. Damage to myelin occurs in diseases such as multiple sclerosis, which compromises nerve signaling and impairs motor and cognitive function. Myelin forms from a...
NeuroEngineering | Postdoctoral Fellowship
Lead Researcher(s): Isaac Kauvar
Our drive to seek new information is powerful. As children, we play — experimenting to establish the relationship between our actions and the environment. As adults, we consume media — searching for news and entertainment. As scientists, we explore — carrying out complicated experiments that probe...
NeuroDiscovery | Postdoctoral Fellowship
Lead Researcher(s): Ernie Hwaun
Cephalopods, including the cuttlefish, octopus, and squid, possess one of the most advanced nervous systems among invertebrates. With their advanced nervous systems, cephalopods are able to perform sophisticated behaviors such as navigating in open water to search for food. Yet how their nervous...
NeuroDiscovery | Postdoctoral Fellowship
Lead Researcher(s): Matt McCoy
Many of the largest, most complex genes in the genome are enriched in the brain and are frequently mutated or misregulated in neurological diseases and disorders such as Alzheimer's disease, autism spectrum disorders, and Rett syndrome. This proposal outlines a detailed study of this distinct class...
NeuroHealth | Postdoctoral Fellowship
Lead Researcher(s): Caitlyn Seim
Vibrotactile stimulation provides powerful somatosensory and proprioceptive input to the nervous system. There is growing evidence that this stimulation may significantly improve limb function after brain injury. However, current technology restricts further research to short, laboratory studies...
NeuroHealth | SIGF - Graduate Fellowship
Lead Researcher(s): Kathryn Wu
Schwann cells (SCs) sort and myelinate peripheral axons, and impairments in either process can cause long-term disability. There are no therapeutic strategies for targeting SC dysfunction, underscoring the need to investigate mechanisms of sorting and myelination. Both processes require highly...
NeuroHealth | SIGF - Graduate Fellowship
Lead Researcher(s): Gustavo Chau
Absence epilepsy is a form of pediatric epilepsy which causes seizures with brief lapses in awareness. Electron microscopy results in a murine model of absence epilepsy support the hypothesis that maladaptive myelination plays a role in disease progression. To enable whole-brain, longitudinal...
NeuroHealth | Neuroscience:Translate
Lead Researcher(s): Christopher Lee-Messer, MD, PhD, Daniel Rubin
Current automated seizure detection software is slow, inaccurate and rarely precise enough for clinicians to rely upon. This project aims to use cutting-edge AI methods to develop a powerful new algorithm that will enable better seizure diagnosis and treatment plan formation.
