![T41B (Thy1-hAPPLond/Swe+ [Line 41])](https://med.stanford.edu/sbfnl/services/dm/dm5/_jcr_content/main/panel_builder/panel_1/text_image.img.320.high.jpg/t41b-3.jpg "T41B (Thy1-hAPPLond/Swe+ [Line 41])")
T41B (Thy1-hAPPLond/Swe+ [Line 41])
T41b transgenic mice show mature amyloid-beta plaques, pathological hallmarks of AD, in the frontal cortex as early as 3-4 months of age and develop plaques in the hippocampus, thalamus, olfactory region, basolateral amygdala, and subiculum at the age of 5-7 months.
PS19 (B6;C3-Tg(Prnp-MAPT*P301S)PS19Vle/J)
PS19 transgenic mice express the P301S mutant form of human tau and develop progressive accumulation of neurofibrillary tangles with age. Thus, the strain is commonly used as a model of tauopathy, such as Alzheimer's Disease.
5XFAD
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Taconic APPSWE
Coming soon...
