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Focal Ischemia (Stroke) Models


MCAO (Experimental Middle Cerebral Artery Ischemia and Functional Recovery)

MCAO (Experimental Middle Cerebral Artery Ischemia and Functional Recovery)

Middle Cerebral Artery (MCA) occlusion involves temporarily or permanently restricting MCA blood flow to the cortex and striatum by inserting intraluminal suture in the internal carotid via an incision in the external carotid. The suture lodges in the junction between the anterior and middle cerebral arteries and remains in place either for a predetermined amount of time or permanently.