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The Phil and Penny Knight Initiative for Brain Resilience

Knight Initiative for Brain Resilience at the Wu Tsai Neurosciences Institute

The Knight Initiative for Brain Resilience envisions a world in which our brains remain fit and healthy as we age.

We are harnessing the collective genius of science and breaking free of established dogma to extend the healthy lifespan of the human brain — building the foundations for a world in which the word “dementia” is forgotten.

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Latest News

Nov 15 2022 Knight Initiative for Brain Resilience
Knight Initiative researchers report that identified novel molecular markers capable of tracking the progression of Parkinson’s disease. Biomarkers for Parkinson’s are currently in short supply and are urgently needed to guide clinical care, support earlier diagnosis, and hasten drug development.
Jul 29 2022 Scope Blog
Tony Wyss-Coray and colleagues have turned up substances in blood that can accelerate or slow down the brain-aging clock. They've identified proteins on blood-vessel surfaces through which some of these molecules can act on the brain, despite the existence of the blood-brain barrier.
May 31 2022 Stanford Medicine
An international collaboration led by Michael Greicius, MD, professor of neurology at Stanford Medicine, has found a rare mutation that protects against Alzheimer’s in individuals who are genetically predisposed to the disease.
May 25 2022 Wu Tsai Neuro
With a new study published in Nature, Wu Tsai Neurosciences Institute researchers are helping to show that the cerebrospinal fluid that bathes our brains holds clues to healthy brain aging.
May 25 2022 Wu Tsai Neuro
Katrin Andreasson discusses how immune cells can cause harmful brain inflammation and contribute to the development of neurodegenerative diseases like Alzheimer’s disease.
Apr 27 2022 Stanford News
A new initiative on brain resilience will study the causes of cognitive decline—what may be done to prevent, delay, or reverse the decline—and what goes right for those who keep their cognitive abilities intact.