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SLM-based methods for 3D control and imaging in the brain - Darcy Peterka

Wu Tsai Neurosciences Institue, seminar series
December 5, 2019 - 12:00pm to 1:00pm
Clark Center Auditorium

Darcy Peterka, PhD 

Senior Scientist and Director of Cellular Imaging in the Zuckerman
Mind Brain Behavior Institute and Director of Technologies,
NeuroTechnology Center,
Columbia University

Host: Jun Ding


Recording neuronal activity throughout the brain with high temporal and spatial resolution may be a critical step in understanding how the brain works. Task-based approaches allow intelligent trade-offs between resolution, speed, and signal. I will describe projective two-photon imaging methods that leverage the spatiotemperal sparseness of neural activity and use holographic multiplexing, and statistical source separation create capable platforms for high-performance imaging with single cell resolution. Similar holographic platforms can also be used to activate ensembles of neurons with single cell precision, and I will describe recent efforts to improve targeting and control in awake behaving animals

Event Sponsor: 
Wu Tsai Neurosciences Institute
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