Gary Glover

My research interests encompass the physics and mathematics of imaging with Magnetic Resonance (MR). My research is directed in part towards exploration of rapid MRI scanning methods using spiral and other non-Cartesian k-space trajectories for dynamic imaging of function. Using spiral techniques, we have developed MRI pulse sequences and processing methods for mapping cortical brain function by imaging the metabolic response to various stimuli, with applications in the basic neurosciences as well as for clinical applications. These methods develop differential image contrast from hemodynamically driven increases in oxygen content in the vascular bed of activated cortex (Blood Oxygen Level Dependent, or BOLD contrast), using pulse sequences sensitive to the paramagnetic behavior of deoxyhemoglobin or to the blood flow changes. Other interests include multimodal imaging using fMRI in conjunction with EEG, fPET, fNIRS, and neuromodulation with tDCS, tACS, TMS and HiFU. Investigating viscoelasticity of human brain using MR Elastography is of interest as an alternative to BOLD contrast for depicting brain activation.