Stanford Neurosciences Institute Seminar Series Presents
Transcriptional regulation in the development of forebrain GABAergic neurons
John Rubenstein, MD, Ph.D
Nina Ireland Distinguished Professor in Child Psychiatry, University of California, San Francisco
Host: Kristin Muench
The transcription factors that regulate forebrain GABAergic development differ from those transcription factors utilized in other regions of the developing CNS. In my talk I will focus on our current studies of transcriptional mechanisms involving the Nkx2-1 and Lhx6 transcription factors, and the genomic regulatory elements (e.g. enhancers and promoters) and the genes downstream of them.