Optically probing the neural basis of perception - Hillel Adesnik

Optically probing the neural basis of perception

Hillel Adesnik, PhD

Assistant Professor of Neurobiology, University of California, Berkeley

Host: Mu Zhou (Sudhof Lab)

Abstract

I will present a new approach to control the activity of ensembles of neuron in the brain with single cell resolution, millisecond precision, and in full 3D. By engineering new opsins optimized for two photon holographic optogenetics, and developing a new optical system capable of stimulating hundreds of neurons distributed in a large volume of the somatosensory cortex, we aim to simultaneously write in and read out the neural codes of elementary sensory percepts.

Curriculum Vitae

Related Papers

[1] Hillel Adesnik and Helen Wills. "Synaptic Mechanisms of Feature Coding in the Visual Cortex of Awake Mice." Neuron. August 2017, Pages 1147–1159.e4. doi.org/10.1016/j.neuron.2017.08.014

[2] Julia Veit, Richard Hakim, Monika P Jadi, Terrence J Sejnowski and Hillel Adesnik. "Cortical gamma band synchronization through somatostatin interneurons." Nature Neuroscience 20, 951–959 (2017). doi:10.1038/nn.4562