Transcriptional regulation in the development of forebrain GABAergic neurons - John Rubenstein

Stanford Neurosciences Institute Seminar Series Presents

Transcriptional regulation in the development of forebrain GABAergic neurons

John Rubenstein, MD, Ph.D

Nina Ireland Distinguished Professor in Child Psychiatry, University of California, San Francisco

Host: Kristin Muench

Abstract

The transcription factors that regulate forebrain GABAergic development differ from those transcription factors utilized in other regions of the developing CNS. In my talk I will focus on our current studies of transcriptional mechanisms involving the Nkx2-1 and Lhx6 transcription factors, and the genomic regulatory elements (e.g. enhancers and promoters) and the genes downstream of them.