Katrin Ingrid Andreasson

Alzheimer’s disease (AD) is the sixth leading cause of death in the United States and there is a tremendous need for improved therapeutic strategies to treat this prevalent neurodegenerative disease. A devastating symptom of AD is progressive memory loss; this particular disease feature has proven difficult to treat. However, research has begun to unravel novel drivers of AD, including the important role the body’s immune system plays in promoting memory loss. 

This team will investigate whether a decline in intestinal immune cell metabolism drives age-related inflammation and cognitive decline. By replacing aged intestinal macrophages with metabolically healthy ones, they hope to develop a novel approach to enhance cognitive resilience.