To understand how sensory information and physiological state integrate to drive decisions and behaviors. Dr. Xiaoke Chen's lab is focusing now on interoception, which is the sense of the physiological condition of the body. This include our abilities to feel hungry or satiated, to sense heightened blood pressure and heart rate during stress, and to discriminate different types of pain.
The goal is to forge an inter-disciplinary collaboration between physicists, biologists, chemists, and translational medical scientists by inventing new ways of visualizing the brain, from individual molecules to neuronal circuits to entire brain regions, from a normally functioning neuron to a diseased brain.
We propose to connect diverse faculty to deepen interdisciplinary understanding of the neural mechanisms supporting addictive choice by combining conceptual, experimental, and clinical approaches that bridge historically disparate fields of inquiry.