Elevated tau in the piriform cortex in Alzheimer's but not Parkinson's disease using PET-MR

Alzheimer's & dementia (Amsterdam, Netherlands)
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Hossein Moein Taghavi, Mahta Karimpoor, Eric K van Staalduinen, Christina B Young, Marios Georgiadis, Samantha Leventis, Mackenzie Carlson, America Romero, Alexandra Trelle, Hillary Vossler, Maya Yutsis, Jarrett Rosenberg, Guido A Davidzon, Greg Zaharchuk, Kathleen Poston, Anthony D Wagner, Victor W Henderson, Elizabeth Mormino, Michael Zeineh
INTRODUCTION: Olfactory dysfunction can be an early sign of Alzheimer''s disease (AD). We used tau positron emission tomography-magnetic resonance (PET-MR) to analyze a key region of the olfactory circuit, the piriform cortex, in comparison to the adjacent medial temporal lobe.'