NeuroHealth
Translating neuroscience discoveries into treatments
Understanding the brain in health and disease will improve treatments for ourselves and our loved ones. Our clinical scientists not only treat patients, but are also working with basic scientists to pioneer novel treatments for psychiatric and neurological disease. Ongoing research aims to reverse brain aging, ease the devastating consequences of stroke, and develop non-invasive treatments to modulate brain activity associated with epilepsy and other neurological diseases. Breakthrough improvements in brain and mental health benefit not just individuals, but society as a whole.
Funded Research - Big Idea
Developing brain organoids – three dimensional brain tissues grown in the lab – to study human brain development, evolution and neuropsychiatric disorders.
Funded Research - Postdoctoral Fellowship
Spinal cord injury (SCI) is a debilitating condition that affects young adults between the ages of 16 and 30, which leads to lifelong medical and financial burdens. SCI still results in a decreased quality-of-life and lower life expectancy for patients. This is due in part to the lack of a regenerative-based therapeutic approach to treating SCI in the clinic.
Funded Research - Neuroscience:Translate
Current automated seizure detection software is slow, inaccurate and rarely precise enough for clinicians to rely upon. This project aims to use cutting-edge AI methods to develop a powerful new algorithm that will enable better seizure diagnosis and treatment plan formation.
Funded Research - Neuroscience:Translate
In light of the dual public health crises of chronic pain and opioids, there is an urgent need to develop non-addictive alternative therapies for chronic pain. This project's goal is to develop a new protocol for transcranial magnetic stimulation — a non-invasive method of neuromodulation — that is optimized for chronic pain treatment.
Funded Research - Neuroscience:Translate
Acute brain inflammation after stroke and head trauma causes adverse health outcomes affecting millions of patients each year in the U.S., and current treatments are insufficient. This project will test a promising new therapy to reduce inflammation by targeting the enzyme OGG1, a potentially important controller of acute inflammatory responses.
This project is jointly supported by the Wu Tsai Neurosciences Institute and SPARK.
Funded Research - Postdoctoral Fellowship
Aging is the number one risk factor for debilitating diseases such as neurodegeneration. Can manipulation of neurons in the brain alter the body’s physiological state to extend lifespan?
Funded Research - Seed Grant
This proposal brings together faculty with this diverse expertise to develop the first gold standard test of auditory-vocal affect. Once developed, validated, and normed, we will deploy this test in the clinical context of autism to quantify impairments and direct neurobiological investigation.
Funded Research - Seed Grant
We will combine the genetics expertise of the Kingsley lab and the neuroscience expertise of the Raymond lab to characterize molecular, cellular, neurophysiological, and behavioral defects in mice engineered to model the risk or protective variants in the human calcium channel gene.
