Knight Initiative Research Community

Birgitt Schuele

Birgitt Schüle, MD, is an Associate Professor in the Department of Pathology at Stanford University School of Medicine. Her research focuses on medical genetics and stem cell modeling to uncover disease mechanisms and pathways involved in neurodegeneration in Parkinson's disease and related disorders. She is dedicated to developing novel therapeutic strategies that contribute to the advancement of precision medicine.

Jonathan Z. Long

Dr. Jonathan Long is an Associate Professor of Pathology and an Institute Scholar of Stanford ChEM-H (Chemistry, Engineering & Medicine for Human Health). His laboratory studies signaling pathways in mammalian energy metabolism. The long-term goal of this program is to discover new molecules and pathways that can be translated into therapeutic opportunities for obesity, metabolic disease, and other age-associated chronic diseases. Work from the laboratory has been recognized by numerous awards from the Alfred P.

Anne Brunet

Dr. Brunet is interested in the molecular mechanisms of aging and longevity, with a particular emphasis on the nervous system. Her lab is interested in identifying pathways involved in delaying aging in response to external stimuli such as availability of nutrients and mates. She also seeks to understand the mechanisms that influence the rejuvenation of old stem cells. Finally, her lab has pioneered the naturally short-lived African killifish as a new model to explore the regulation of aging and age-related diseases.

Monther Abu-Remaileh

The Abu-Remaileh Lab is interested in identifying novel pathways that enable cellular and organismal adaptation to metabolic stress and changes in environmental conditions. We also study how these pathways go awry in human diseases such as cancer, neurodegeneration and metabolic syndrome, in order to engineer new therapeutic modalities.

Takeshi Uenaka

Takeshi Uenaka is a neurologist and neuroscientist studying neurodegenerative diseases by using human stem cell-derived neuron, astrocyte, and microglia. Takeshi received his medical degree from Kobe University, Japan, in 2007 and worked for 10 years as a neurologist. He completed his Ph.D. in neuroscience at Kobe University Graduate School of Medicine, Japan, in 2019. As a postdoctoral fellow with Dr. Marius Wernig, he is working to model disease environment in vitro having the above 3 cell types and to assess the interaction between microglia and intraneuronal protein aggregation.

Ravi Nath

Ravi Nath is investigating mechanisms that promote resilience to neurodegenerative diseases. As a postdoctoral scholar in Anne Brunet’s lab, Ravi is pioneering an emerging short-lived vertebrate model system—the African turquoise killifish—to investigate the role of sleep in aging and neurodegenerative diseases. Ravi built a longitudinal tracking system to explore how sleep changes across lifespan and in the context of neurodegenerative disease.

Yi Zeng

Yi studies the mechanisms of neurodegeneration as a postdoctoral scholar in the laboratory of Professor Aaron Gitler. He completed his Ph.D. in Cell and Molecular Biology from the University of Chicago under the supervision of Prof. Jon Staley. At Uchicago, Yi studied the mechanisms of co-transcriptional splicing and RNA export. At Stanford, he is studying how RNA processing is misregulated during neurodegeneration, focusing on Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal dementia (FTD).

Chiara Anselmi

My expertise is in the areas of regeneration, evolution, the nervous system and cell biology. I use a marine colonial tunicate, Botryllus schlosseri, characterized by having robust regenerative capabilities and an assayable and frequent (weekly) CNS (Central nervous system) tissue regeneration and loss throughout adult life. I believe that comparative studies on a simple chordate can help us elucidate the principal mechanisms that are the foundation of regeneration and aging.

Daniela Rojo Capitanio

Daniela Rojo is a genetic neuroscientist studying gene expression regulation in myelin-forming glia. As a postdoctoral fellow in the group of Dr. Erin Gibson, Daniela aims to decipher the role of the molecular circadian clock in myelin-forming glia and evaluate how its genetic disruption affects neurodegenerative disorders of dysregulated myelination like multiple sclerosis. From Argentina, Daniela Rojo completed her PhD at the Institute of Research in Genetic Engineering and Molecular Biology in Buenos Aires under the supervision of Dr. Marcelo Rubinstein.

Subscribe to Knight Initiative Research Community