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Exploring the brain's navigation system with high-resolution imaging and virtual reality - Daniel Dombeck

October 22, 2015 - 12:00pm to 1:00pm
Clark Center Auditorium

Stanford Neurosciences Institute Seminar Series Presents

 

Exploring the brain's navigation system with high-resolution imaging and virtual reality

 

Daniel Dombeck, Ph.D

 

Assistant Professor, Northwestern University

Host: Caitlin Mallory 

Abstract

I will discuss techniques that allow us to perform cellular and subcellular resolution imaging of neuronal activity in mice navigating in virtual reality environments and recent results from imaging place cells and grid cells. I will describe activity paHerns that we have observed in hippocampal place cell dendrites and the implications for how associative Hebbian learning may take place during behavior. I will also describe the functional micro-organization of grid cells in the medial entorhinal cortex and what the organization might tell us about the circuits that generate grid cell firing patterns.

Recent Papers:

[1] The functional micro-organization of grid cells reveal by cellular-resolution imaging   James G. Heys, Krsna V. Rangarajan, Daniel A. Dombeck Neuron. 2014 Dec 3;84(5):1079-90. doi:10.1016/j.neuron.2014.10.048

[2] Calcium transient prevalence across the dendritic arbour predicts place field properties Mark E. J. Sheffield, Daniel A. Dombeck Nature. 2015 Jan 08;517:200-04. doi:10.1038/nature13871Curriculum Vitae

A conversation with Daniel Dombeck and the Stanford group NeuWrite West can be streamed or downloaded: Dombeck Conversation

Lab Website

Event Sponsor: 
Stanford Neurosciences Institute
Contact Email: 
neuroscience@stanford.edu
Contact Phone: 
650-497-8019

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