Knight Initiative News

Andreasson received the Inge Grundke-Iqbal Award for her work on restoring cognition in Alzheimer's. Karly Cody, a postdoctoral fellow in the lab of Knight Initiative researcher Elizabeth Mormino, was also honored.

Stanford neuroscientist Sergiu Pasca is pioneering technology to recreate human brain tissue and neural circuits in the lab – giving scientists unprecedented access to human brain development and opening new possibilities for treating disorders from psychiatric disease to chronic pain.

New tools that reveal how neuron-specific waves travel through the brains of mice in real time hold promise for understanding diseases such as epilepsy and Alzheimer’s, and open avenues for advances in neuroscience and AI.

Is your brain aging faster than your chronological age? New research shows it could raise your risk of death and dementia significantly—and offers promise for early intervention.

Knight Initiative-funded research ran the gamut from chemistry to public health, but one theme brought it all together: Studying what makes the brain resilient will help more people live better lives.

The findings of two recent studies give hope that the disease could one day be reversed in humans—but experts warn that this complex disease will likely need multiple complementary treatments.

A new Stanford study used blood proteins to analyze the 'biological' age of brains and other organs compared to the person's actual age.

The tool, built by a team led by Stanford's Tony Wyss-Coray, uses a single vial of blood to assess the 'biological age' of each organ.

A blood-test analysis developed at Stanford Medicine can determine the “biological ages” of 11 separate organ systems in individuals’ bodies and predict the health consequences.

Research in mice indicates that inhibiting the LRRK2 enzyme could stabilize patients with a type of Parkinson’s disease.

Scientists in the lab of chemical engineer Monther Abu-Remaileh are uncovering the cellular functions that go awry in degenerative brain disorders and identifying therapies that could treat them.

A decade ago, three generations of Stanford scientists banded together to publish a landmark study on one of the brain’s most prevalent structures. Today, Wu Tsai Neurosciences Institute researchers are discovering that myelin is key to just about every aspect of neurological health.

Cancer treatment with a cell-based immunotherapy causes mild cognitive impairment, according to research by Wu Tsai Neuro affiliate Michelle Monje and colleagues. They also identified compounds that could treat it.

Improving cells’ ability to sort and recycle components—including cholesterol—could lead to therapies for a wide range of neurodegenerative conditions.

This week on the podcast, Stanford cell biologist Brad Zuchero takes us on a tour of the frontiers of glia-science

A new analysis of a vaccination program in Wales by a Knight Initiative–supported team found that the shingles vaccine appeared to lower new dementia diagnoses by 20% — more than any other known intervention.

Knight Initiative–supported research by Pascal Geldsetzer and colleagues adds to evidence that preventing the viral infection can help stave off cognitive decline.

New Alzheimer's biomarkers focus on whether Alzheimer's has actually begun to affect a person's thinking and memory, rather than just amyloid levels.

This week on the podcast, Stanford psychiatry professor Erin Gibson joins us again to share the latest findings on sleep, myelin, and neurodegenerative disease.

Stanford researchers have created a compound that relieves multiple types of pain in mice without building tolerance or causing psychoactive side effects.