Neuroscience News

A new study finds links between two popular models of the disease—and the results could change how researchers think about treatment.

Small cell lung cancer often metastasizes to the brain. A Stanford Medicine-led study shows the cancer cells form synapses with neurons, and signaling across these synapses encourages tumor growth.

A study of killifish reveals how protein dysfunction develops in vertebrate brain cells, a key driver of aging – shedding light on cognitive decline and dise

Stanford researchers reviewed over 400 therapy evaluations and discovered a crucial mismatch: Mouse studies test disease prevention, while human trials test treatment of existing disease.

Knight Initiative researchers used a new lab model of aging human neurons to show that as cells age, lysosomes fall into disrepair and waste builds up—feeding a damaging cycle that could lead to Alzheimer’s.

Stanford Medicine researchers discuss the brain’s ancient wiring and how its built-in reward-seeking system can be hijacked by addiction—as well as ways to prevent and treat it.

The Global Neurodegeneration Proteomics Consortium gathered a trove of data on potential signs of neurological disease—and researchers including Knight Initiative director Tony Wyss-Coray are already using it to make new discoveries.

An interdisciplinary team of Wu Tsai Neuro scientists working on balls of human neurons called organoids wanted to scale up their efforts and take on important new questions. The solution was all around them.

Research from the Giocomo lab finds that mice create neural maps of the location of rewards, distinct from the well-known hippocampal maps of an animal's location in space.

Scientists found that humans and mice share persistent brain-activity patterns in response to negative sensory inputs – offering insight into emotion and potential links to neuropsychiatric disorders.

Knight Initiative researchers discover a biomarker in spinal fluid that could help forecast Alzheimer’s progression and improve clinical trials.

By studying never-before-seen details of brain connectivity in human infants, researchers at the Wu Tsai Neurosciences Institute have identified how a balance of innate structure and flexible learning produces our remarkably organized visual brains.

New research from the Malenka lab reveals that reward-based learning requires the two neuromodulators to balance one another's influence.

A collaboration between Institute Faculty Scholars Julia Kaltschmidt and Todd Coleman has identified a key step in nervous system control over gut motility, opening new opportunities for understanding GI disorders in premature infants

Institute affiliates Brad Zuchero, Justin Du Bois and colleagues discovered that neurons require signaling from glia to become fully excitable, rather than by becoming excitable by default.

Groundbreaking research supported by the Knight Initiative for Brain Resilience at Stanford’s Wu Tsai Neurosciences Institute deepens our understanding of how the amino acid taurine may help reduce appetite and prevent obesity.