Melanie Hayden Gephart

Melanie Hayden Gephart

Professor - University Medical Line, Neurosurgery
Professor - University Medical Line (By courtesy), Neurology
Member, Bio-X
Member, Maternal & Child Health Research Institute (MCHRI)
Member, Stanford Cancer Institute
Member, Wu Tsai Neurosciences Institute
Neurosurgery Residency, Stanford University (2014)
MD, University of California at San Diego (2007)
Board Certification: American Board of Neurological Surgery, Neurosurgery (2018)
Masters of Advanced Sciences, University of California at San Diego, Clinical Research (2007)
BS, University of California at San Diego, Neuroscience and Physiology (2001)
I am a brain tumor neurosurgeon, treating patients with primary and metastatic brain tumors. I treat patients with malignant and benign tumors, including glioma, brain metastases, meningioma, and vestibular schwannomas. I direct the Stanford Brain Tumor Center and the Stanford Brain Metastasis Consortium, collaborative unions of physicians and scientists looking to improve our understanding and treatment of brain tumors. My laboratory seeks greater understanding of the mechanisms driving tumorigenesis and disease progression in malignant brain tumors. We study how rare cancer cell populations survive and migrate in the brain, inadvertently supported by native brain cells. We develop novel cell free nucleic acid biomarkers to track brain cancer treatment response, relapse, and neurotoxicity. Our bedside-to-bench-to-bedside research model builds on a foundation of generously donated patient samples, where we test mechanisms of brain cancer growth, develop novel pre-clinical models that reliably recapitulate the human disease, and facilitate clinical trials of new treatments for patients with brain cancer.