Sergiu P. Pasca

This study will introduce a vascular-like electronic system that merges seamlessly with neural organoids, establishing an integrated vascular-electronic-neural network. This envisaged platform holds the promise of heralding a transformative phase in the evolution of human neural organoid research and elucidating the fundamental understanding on the roles of oxygen and nutrient perfusion during neural development.

The Stanford Brain Rejuvenation Project is an initiative by leading aging researchers, neuroscientists, chemists, and engineers to understand the basis of brain aging and rejuvenation and how they relate to neurodegeneration.

Dr. Iram will use brain intrinsic and systemic regulators of aging, in an attempt to accelerate maturation of human-derived brain organoids. This has the potential to produce the first ever aged human brain 3D cultures and identify factors which accelerate brain aging.