Knight Initiative News

An interdisciplinary team of Wu Tsai Neuro scientists working on balls of human neurons called organoids wanted to scale up their efforts and take on important new questions. The solution was all around them.

A blood-test analysis developed at Stanford Medicine can determine the “biological ages” of 11 separate organ systems in individuals’ bodies and predict the health consequences.

Research in mice indicates that inhibiting the LRRK2 enzyme could stabilize patients with a type of Parkinson’s disease.

Former Wu Tsai Neuro Interdisciplinary Postdoctoral Scholar Sergey Stavisky helped lead an effort to translate brain signals into speech.

A new study supported by the Knight Initiative for Brain Resilience reveals how Alzheimer's disease and attention shape our ability to remember.

Research from the Giocomo lab finds that mice create neural maps of the location of rewards, distinct from the well-known hippocampal maps of an animal's location in space.

Researchers supported by a Neuroscience:Translate grant from Wu Tsai Neuro have developed a new technology for removing blood clots that is more than twice as effective as current techniques.

Scientists found that humans and mice share persistent brain-activity patterns in response to negative sensory inputs – offering insight into emotion and potential links to neuropsychiatric disorders.

Knight Initiative researchers discover a biomarker in spinal fluid that could help forecast Alzheimer’s progression and improve clinical trials.

Cancer treatment with a cell-based immunotherapy causes mild cognitive impairment, according to research by Wu Tsai Neuro affiliate Michelle Monje and colleagues. They also identified compounds that could treat it.

Improving cells’ ability to sort and recycle components—including cholesterol—could lead to therapies for a wide range of neurodegenerative conditions.

In a new study, researchers created an AI model of the mouse visual cortex that predicts neuronal responses to visual images.

Researchers with the Wu Tsai Neuro–funded Stanford Brain Organogenesis project have rebuilt, in laboratory glassware, the neural pathway that sends information from the body’s periphery to the brain.

A new analysis of a vaccination program in Wales by a Knight Initiative–supported team found that the shingles vaccine appeared to lower new dementia diagnoses by 20% — more than any other known intervention.

Psychiatrist Anna Lembke shares what scientists have discovered so far about the potential for GLP-1s in addiction treatment.

By studying never-before-seen details of brain connectivity in human infants, researchers at the Wu Tsai Neurosciences Institute have identified how a balance of innate structure and flexible learning produces our remarkably organized visual brains.

Stanford researchers have created a compound that relieves multiple types of pain in mice without building tolerance or causing psychoactive side effects.

New findings about the sugary armor on the brain’s frontline cells could shed light on cognitive decline and diseases like Alzheimer’s—and open new avenues for treatment.

 

Wu Tsai Neuro faculty scholar Guosong Hong explains how he and colleagues have used a dye commonly found in nacho chips to make living tissue transparent.

Stanford Medicine research demonstrates a new way of detecting cells implicated in the malfunctions that cause psychiatric diseases.