Neuroscience News

Stanford researchers reviewed over 400 therapy evaluations and discovered a crucial mismatch: Mouse studies test disease prevention, while human trials test treatment of existing disease.

Knight Initiative researchers used a new lab model of aging human neurons to show that as cells age, lysosomes fall into disrepair and waste builds up—feeding a damaging cycle that could lead to Alzheimer’s.

Stanford Medicine researchers discuss the brain’s ancient wiring and how its built-in reward-seeking system can be hijacked by addiction—as well as ways to prevent and treat it.

The lab’s second crop of pilot awards will foster research in visual attention, the neurophysiology of exercise, and therapies for autism and mild cognitive impairment associated with aging.

Andreasson received the Inge Grundke-Iqbal Award for her work on restoring cognition in Alzheimer's. Karly Cody, a postdoctoral fellow in the lab of Knight Initiative researcher Elizabeth Mormino, was also honored.

Stanford neuroscientist Sergiu Pasca is pioneering technology to recreate human brain tissue and neural circuits in the lab – giving scientists unprecedented access to human brain development and opening new possibilities for treating disorders from psychiatric disease to chronic pain.

The Global Neurodegeneration Proteomics Consortium gathered a trove of data on potential signs of neurological disease—and researchers including Knight Initiative director Tony Wyss-Coray are already using it to make new discoveries.

An interdisciplinary team of Wu Tsai Neuro scientists working on balls of human neurons called organoids wanted to scale up their efforts and take on important new questions. The solution was all around them.

Knight Initiative-funded research ran the gamut from chemistry to public health, but one theme brought it all together: Studying what makes the brain resilient will help more people live better lives.

Stanford neurobiologist Carla Shatz, famous for discovering how neural connections develop early in life, is using that knowledge to work on the problem of how they can later deteriorate from Alzheimer’s disease.

A decade ago, three generations of Stanford scientists banded together to publish a landmark study on one of the brain’s most prevalent structures. Today, Wu Tsai Neurosciences Institute researchers are discovering that myelin is key to just about every aspect of neurological health.

Research from the Giocomo lab finds that mice create neural maps of the location of rewards, distinct from the well-known hippocampal maps of an animal's location in space.

Wu Tsai Neuro researcher Karl Deisseroth and colleagues drew on a variety of techniques to probe how emotional responses arise in the brain.

Scientists found that humans and mice share persistent brain-activity patterns in response to negative sensory inputs – offering insight into emotion and potential links to neuropsychiatric disorders.

Knight Initiative researchers discover a biomarker in spinal fluid that could help forecast Alzheimer’s progression and improve clinical trials.

Wu Tsai Neuro faculty scholar Laura Gwilliams is unlocking how the brain turns sound into meaning.