Browse wide-ranging research at the frontiers of neuroscience supported by Wu Tsai Neurosciences Institute grants, awards, and training fellowships.
Projects
The molecular and cellular basis of magnetosensation: quantum effects in biological systems
For decades we have known that a wide variety of animals use the earth’s magnetic field for navigation, although the means by which they sense it has remained a mystery. There is a long-standing idea that animals like migratory birds use small magnetic deposits in their beaks to act as a compass, however, this idea remains unverified and is currently questioned by many in the field.
The NeuroFab: The hub for new ideas in neuro-engineering
Creating an incubator for next-generation neural interface platforms.
The role of non-canonical GABA synthesis in midbrain dopamine neurons on striatal inhibition
Due to the critical role that dopamine producing neurons play in pathophysiology, it is important to examine the function of its co-released GABA. This research aims to study GABA biosynthesis in midbrain dopamine producing neurons and it’s effect on striatal inhibition.
Understanding cellular responses induced by chronic implantation of electrodes using a novel human neural differentiation platform
Electrodes implanted in the brain have great potential, with applications in neurodegenerative disease, brain-computer interfaces, and more. However, the presence of electrodes in brain tissue causes a response known as gliosis, in which a scar forms around the electrode, reducing its effectiveness and access to neurons.
Controlling schistosomiasis via CRISPR/CAS9-mediated gene drive
Schistosomiasis is a parasitic disease second only to malaria in its human health and economic impact on tropical nations.
Modelling the Pupil Light Reflex for Non-Image Forming Vision
Although you’re aware of the light that you see, light also affects us in ways that you might not appreciate. These so called “non-image forming” (NIF) pathways were recently discovered, they start in the human eye before projecting to over a dozen brain regions. They modulate aspects of human function including our daily rhythms, our sleep patterns, the way we feel and the way we think.