Knight Initiative News

Some of the 17 million Americans afflicted with major depressive disorder each year may soon receive a surprising new prescription from their clinician: Have fun on a virtual reality device.

Inside the brains of people with psychosis, two key systems are malfunctioning: a “filter” that directs attention toward important external events and internal thoughts, and a “predictor” composed of pathways that anticipate rewards.

Pro-inflammatory protein TREM1 in peripheral immune cells may promote age-related cognitive decline and dementia, according to Knight Initiative–funded research.

Wu Tsai Neuro research suggests giant genes could hold the key to the development of complex nervous systems across the animal kingdom.

New research supported by Wu Tsai Neurosciences Institute could lead to novel treatments for demyelinating disorders such as multiple sclerosis.

Recent research supported by the Knight Initiative has identified a link between lipid droplets in the microglia to a known genetic risk factor for AD.

Two new studies supported by the Knight Initiative highlight groundbreaking new early biomarkers for the diagnosis and treatment of neurodegenerative disease.

Research supported by the Knight Initiative found that metformin, a commonly prescribed diabetes drug associated with moderate weight loss, stimulates the production of lac-phe, a molecule abundant after exercise.

Dentate spikes in the rodent hippocampus support learning by linking introspective thoughts and memories with current circumstances, according to new research supported by the Wu Tsai Neurosciences Institute.

Disabling the notorious APOE4 gene might protect against the disease, according to research from Michael Greicius and team.

A new AI model developed by Wu Tsai Neuro affiliate Vinod Menon and team can distinguish between male and female brains, playing a crucial role in human brain development, aging, and the manifestation of psychiatric and neurological disorders.

For those with stroke, involuntary contractions of the hands and arms often follow. A simple, wearable vibrating glove developed by Wu Tsai Neuro affiliates Allison Okamura, Caitlin Seim and others, may offer a more effective treatment.

Even just one night of less than six hours of rest can impair short-term memory according to experts, including Wu Tsai Neuro affiliate Sharon Sha.

A new study in rats by Institute affiliate Raag Airan — supported by a Wu Tsai Neuro seed grant — looked at whether ketamine’s effects depend on opioid pathways and uncovered a surprising difference between males and females.

Learn about the experience of several participants in the BrainGate brain-computer interface clinical trial, and the large team effort by Wu Tsai Neuro affiliates Jaimie Henderson, Paul Nuyujukian, and the late Krishna Shenoy over the past decade to get n

In a study supported by Wu Tsai Neuro's Neurochoice Initiative, researchers have delved into the complex relationship between brain activity and the risk of relapse in individuals recovering from stimulant addiction.

Inspired by Japanese paper art, a new device can record from 3D ‘organoid’ models of the developing human brain for months without disturbing their growth or structure.

Stanford Hospital brings together two autopsy rooms, the morgue, including bereavement and viewing rooms, as well as decedent care team offices. The new space allows for more advanced research for the Knight Initiative for Brain Resilience and others.

Stanford Medicine researchers, including Wu Tsai Neuro affiliate Nolan Williams, find that ibogaine, a plant-based psychoactive compound, safely led to improvements in depression, anxiety and functioning among veterans with traumatic brain injuries.

Stanford Medicine scientists, including Wu Tsai Neuro affiliates David Spiegel and Nolan Williams, used transcranial magnetic stimulation to temporarily enhance hypnotizability in patients with chronic pain, making them better candidates for hypnotherapy.