Knight Initiative News

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

Proteins that start life inside neurons build up faster in old age and spread to other brain cells—a potential source of neurological mischief

Knight Initiative Director Tony Wyss-Coray and others talked to Nature Aging about aging research

Unlike chronological age, biological age can change and is a reflection of how your body's cells, tissues, and organs are functioning and aging

The database of lysosomal proteins is already helping researchers study how brain cells’ waste and recycling systems work—or don’t—in Alzheimer’s and other neurological diseases

From studying post-viral fatigue to engineering transparent mouse brains, round three of the Wu Tsai Neurosciences Institute’s Big Ideas grants will push the bounds of what’s possible

We speak with neurologist Katrin Andreasson about new links between inflammation, metabolism and new hopes for treating neurodegeneration

Stanford Data Science and the Wu Tsai Neurosciences Institute launched the Center for Neural Data Science as a collaborative hub to accelerate discovery in neuroscience and train the next generation of data-driven neuroscientists

If the results are confirmed, an expert said, the Knight Initiative-funded research "would be groundbreaking for dementia"

A new study from Knight Initiative researchers suggests that the two-dose shingles shot also may slow the progression of dementia

A Knight Initiative-funded project says shingles vaccination could protect you from getting dementia or slow the progression of the disease

Knight Initiative scientists report that biology, behavior, and circumstance all intertwine over a lifetime to influence how organs grow old

Everything we know now, and what we hope and pray is coming

Amyotrophic lateral sclerosis and frontotemporal dementia are devastating neurodegenerative diseases. Knight Initiative postdoc Yi Zeng is working to understand the role a central protein plays in both diseases—and whether it might point toward new diagnostics and treatments

Neuroradiologist Raag Airan and his lab have found a non-invasive, drug-free method to help clean the brain, reduce inflammation, and treat disease—and with Knight Initiative for Brain Resilience support, they plan to test it in people soon.

The Knight Initiative’s Fall Symposium featured researchers building new molecular atlases of the brain alongside new updates on neurodegenerative disease and what might be done about it.

Research from Knight Initiative Director Tony Wyss-Coray's lab show that an Alzheimer's hallmark—myriad oily droplets in brain cells called microglia—may help connect several of the disorder’s better known but not well understood features.

Neurons are built to last, but with age, bad things can happen to them. Wu Tsai Neuro affiliate Katrin Andreasson's work shows a lot of it is triggered by what’s happening to immune cells outside of the brain.

Amyloid plaques have long been the focus of Alzheimer’s therapies. But Wu Tsai Neuro's Emmanuel Mignot and others are focusing on the stringy tangles of a protein called tau, the unsung second hallmark of Alzheimer’s.

Anne Brunet will receive a Director's Pioneer Award, and Bianxiao Cui will receive a Director's Transformative Research Award.