Funded Research Projects
NeuroHealth | SIGF - Graduate Fellowship
Lead Researcher(s): Angela Y. Lee
Mental illnesses like bipolar disorder affect millions of people around the world, but early symptoms are often difficult to detect. Working across the disciplines of clinical psychology, communication, and computer science, my research will develop a novel computational tool to identify signals of...
NeuroHealth | SIGF - Graduate Fellowship
Lead Researcher(s): Kwamina Nyame
Phospholipid dysregulation is implicated in the pathogenesis of lysosomal storage disorders (LSDs). We found that glycerophosphodiesters (GPDs) accumulate in lysosomes derived from Batten disease models, a life-limiting LSD whose pathological mechanism remains elusive. GPDs are the degradation...
NeuroHealth | SIGF - Graduate Fellowship
Lead Researcher(s): Xianghao Zhan
Traumatic brain injury (TBI) has become a global health hazard. If undetected, the brain damage of TBI can accumulate, calling for better TBI modeling and warning systems. TBI modeling involves three stages: head impact kinematics, brain deformation, and injuries. This project will leverage machine...
NeuroHealth | Neuroscience:Translate
Lead Researcher(s): Peter L. Santa Maria, MBBS, PhD, Guosong Hong
Sensorineural hearing loss is an increasingly prevalent condition that causes disability to over a third of US adults aged over 65. This team is developing a breakthrough device to restore high-frequency hearing that preserves residual hearing through a reversible and minimally invasive approach.
NeuroHealth | Neuroscience:Translate
Lead Researcher(s): Helen Bronte-Stewart, MD, MS, Allison Okamura
This team is developing a device that will enable accurate diagnosis of Parkinson’s disease via telemedicine. They initially introduced the technology of Quantitative DigitoGraphy (QDG) using a repetitive alternating finger tapping (RAFT) task on a musical instrument digital interface (MIDI)...
NeuroHealth | Neuroscience:Translate
System uses computer vision algorithms and emotion classifiers integrated into gameplay to detect emotion in the child’s face via the phone’s front camera to determine agreement with the displayed prompt, along with other features such as gaze, eye contact, and joint attention.
NeuroHealth | Neuroscience:Translate
This team will use their Neuroscience:Translate award to develop small-molecule therapeutics with immunomodulatory properties linked to Parkinson’s disease and test their potentially therapeutic effects in cell cultures and animal models of the disease.
NeuroHealth | Neuroscience:Translate
Lead Researcher(s): Kim Bullock, MD, Jeremy Bailenson
This team has created an extended reality–enhanced implementation of "behavioral activation," one of the most effective forms of evidence-based psychotherapy for major depression. They will use the Neuroscience:Translate award to test the efficacy and scalability of this approach and accelerate the...
NeuroHealth | Neuroscience:Translate
Lead Researcher(s): Jon-Paul Pepper, MD, Philip Beachy
This team has identified a small-molecule drug pathway that can improve functional recovery from nerve injury. The team will use the Neuroscience:Translate funds to test several approaches to topically apply this compound directly to damaged nerves during surgery to safely improve patient outcomes.
NeuroDiscovery | Postdoctoral Fellowship
Lead Researcher(s): Elizabeth DuPre
Cognitive neuroscience has traditionally focused on identifying the neural basis of psychological traits or state effects across large samples of participants. Recently, researchers have pushed towards providing more precise estimates of individual functional organization to better understand both...
