Knight Initiative News

Neurons are built to last, but with age, bad things can happen to them. Wu Tsai Neuro affiliate Katrin Andreasson's work shows a lot of it is triggered by what’s happening to immune cells outside of the brain.

A new study led by Wu Tsai Neuro Faculty Scholar Laura Gwilliams maps how we simultaneously process different words.

Organizers of the Wu Tsai Neurosciences Institute’s 12th annual symposium share exciting new discoveries from the frontiers of the “gut-brain axis.”

Amyloid plaques have long been the focus of Alzheimer’s therapies. But Wu Tsai Neuro's Emmanuel Mignot and others are focusing on the stringy tangles of a protein called tau, the unsung second hallmark of Alzheimer’s.

Anne Brunet will receive a Director's Pioneer Award, and Bianxiao Cui will receive a Director's Transformative Research Award.

With large-scale neuron recordings and sharper fMRI now routine, a new collaboration between the Wu Tsai Neurosciences Institute and Stanford Data Science aims to make sense of the surge in data.

In which we discuss the neuroscience of sketching ideas with Stanford psychologist Judy Fan

Untangling the complex connections between the gut, brain and microbiome to heal chronic GI conditions

What could make a promising approach to psychiatry and brain research even better? A solid beat.

The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.

A new study finds links between two popular models of the disease—and the results could change how researchers think about treatment.

Small cell lung cancer often metastasizes to the brain. A Stanford Medicine-led study shows the cancer cells form synapses with neurons, and signaling across these synapses encourages tumor growth.

Knight Initiative researchers are uncovering the fine points of how our brains learn to move. In the long run, their findings could help devise better treatments for Parkinson's disease.

Stanford undergrads and local community college students paired with Wu Tsai Neurosciences Institute researchers to find new ways to head off strokes, predict Alzheimer's disease, and more.

A study of killifish reveals how protein dysfunction develops in vertebrate brain cells, a key driver of aging – shedding light on cognitive decline and diseases like Alzheimer’s, Parkinson’s, and ALS.

Knight Initiative researchers used a new lab model of aging human neurons to show that as cells age, lysosomes fall into disrepair and waste builds up—feeding a damaging cycle that could lead to Alzheimer’s.

Blood and cerebrospinal fluid markers tied to inflammation and metabolism sort some patients into subgroups, according to Knight Initiative researchers, a step toward predicting progression and tailoring care.

The technique, which used genetically healthy donor cells, prolonged life and function in mice with a disease similar to Tay-Sachs. It may help with other neurodegenerative diseases like Alzheimer’s.

The lab’s second crop of pilot awards will foster research in visual attention, the neurophysiology of exercise, and therapies for autism and mild cognitive impairment associated with aging.

Andreasson received the Inge Grundke-Iqbal Award for her work on restoring cognition in Alzheimer's. Karly Cody, a postdoctoral fellow in the lab of Knight Initiative researcher Elizabeth Mormino, was also honored.