The goal is to forge an inter-disciplinary collaboration between physicists, biologists, chemists, and translational medical scientists by inventing new ways of visualizing the brain, from individual molecules to neuronal circuits to entire brain regions, from a normally functioning neuron to a diseased brain.
We propose to connect diverse faculty to deepen interdisciplinary understanding of the neural mechanisms supporting addictive choice by combining conceptual, experimental, and clinical approaches that bridge historically disparate fields of inquiry.
We aim to develop a noninvasive method to produce on-demand and dynamically programmable light emission patterns throughout the entire brain of live mice. The emission patterns can be controlled by brain-penetrant focused ultrasound and switched with millisecond precision for rapid brain-wide optogenetic screening of different brain regions.