Dr. Longo received his MD, and PhD in Neuroscience from the University of California, San Diego. Following an internship in medicine at New York University, he trained as a resident in neurology at the University of California, San Francisco where he also completed a fellowship in neurobiology. He joined the UCSF faculty and eventually served as professor and vice chair of UCSF’s Department of Neurology. Before joining Stanford Medicine in 2006, Dr. Longo was the H. Houston Merritt Professor and Chair of Neurology at the University of North Carolina – Chapel Hill.

At Stanford Medicine, Dr. Longo is the George E. and Lucy Becker Professor of Neurology and Professor, by courtesy, of Neurosurgery. He served as the Chair of the Department of Neurology and Neurological Sciences from 2006 to 2023. Along with his colleagues, he focuses on building programs in neurology and the neurosciences.

His interests include translational research in neurodegenerative disease prevention and therapeutics, providing patient care in the Stanford Health Care Memory Disorders Clinic, and mentoring medical students and other trainees.

Dr. Longo is the 2015 recipient of the inaugural Melvin R. Goodes Prize for Excellence in Alzheimer’s Drug Discovery from the Alzheimer’s Drug Discovery Foundation, and his team’s work on Alzheimer’s therapeutics was featured on the cover of Time Magazine in 2016. He currently serves on the National Advisory Council on Aging for the National Institute on Aging at the NIH.