Funded Projects

This team will use their Neuroscience:Translate award to employ a novel therapeutic technique to correct pathogenic mutations causing Parkinson’s disease.

This team aims to revolutionize future stroke treatment both in clinics and at home by combining a brain-computer interface and augmented reality (AR) into a single rehabilitation platform.

This team aims to advance augmentative and alternative communication technology for people with communication disorders and enable new forms of human-computer interaction by combining novel materials science with modern machine learning.

This team will use their Neuroscience:Translate award to develop an entirely new class of ischemic stroke treatment device that will lead to improved clot extraction to improve the success of endovascular thrombectomy.

This team will use their Neuroscience:Translate award to develop the first wearable ultrasound (US) device for the treatment of inflammatory diseases, such as Rheumatoid Arthritis (RA) and Inflammatory Bowel Disease.

We propose a new line of research whose goal is to examine the druggability of a protein-protein interface involving ApoE, an apolipoprotein whose gene variants represent the strongest genetic risk factor for AD.

People with Parkinson’s Disease (PD) have different types of bacteria in their guts compared to people without neurological diseases. We will study which gut bacteria for people with PD to gain a better understanding of how gut bacteria contribute to inflammation in the body and in the brain or people with this condition. 

We propose to apply mass spectrometry techniques to measure BHB-Phe and other KD metabolites in children undergoing KD for refractory epilepsy at Stanford. Further, in a mouse model of refractory genetic epilepsy, we will compare targeted BHB-Phe treatment to full KD treatment using transcriptomics, EEG assessment of seizures and cognitive testing.

Why do all our brains mature and age in different ways, leading to different cognitive and behavioral outcomes? We envision a novel method that “copies” the information from the RNAs made by the neurons to sensor RNAs we artificially introduce into live animals. 

In this study, we aim to (i) perform a feasibility study to determine the acceptance and feasibility of performing such recordings in the AN and ARFID eating disorders population and (ii) test the hypothesis that the electrophysiologic monitoring of the brain and stomach is associated with a clinically validated behavioral measure of interoception involving water distention of the stomach.

The Stanford Brain Rejuvenation Project is an initiative by leading aging researchers, neuroscientists, chemists, and engineers to understand the basis of brain aging and rejuvenation and how they relate to neurodegeneration.

Breaches barriers in our understanding of stroke to develop therapies and improve stroke recovery.

    More than 60 million people in the United States currently suffer from a serious mental illness, and the associated financial, productivity and human suffering costs are only projected to rise in the near future.

The ability to ignore distracters is impaired for individuals with psychosis. This impairment negatively impacts treatment effectiveness and the ability of individuals with psychosis to function fully.

Continuous blood flow to the brain is needed for neural tissues to survive. Noninvasive imaging of cerebral blood flow (CBF) in humans is challenging, but is critically useful to understand normal brain physiology and to help patients with cerebrovascular disorders such as stroke.

The aim of this project is to improve the accuracy and reliability of dMRI fiber tracking through comparison with a gold standard that unambiguously relates the measured water diffusion patterns to the underlying tissue structure.

StrokeCog is focused on cognitive problems after stroke. The team leads a study aimed at identifying if neuroinflammation plays an important role in the development of post-stroke cognitive decline.