Big Ideas in Neuroscience

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Cross-disciplinary teams transforming our understanding of the brain

Big Ideas are the Wu Tsai Neurosciences Institute's flagship research projects. These five-year grants catalyze cross-disciplinary teams of researchers to collaboratively tackle fundamental questions that advance our understanding of the mind, brain and behavior in health and disease.


Our Big Ideas projects include bold projects to advance our understanding of the science of addiction and brain rejuvenation, to design new technologies to interface with the brain, and to build research platforms to connect molecular to systems-level neuroscience and advance the study of human brain organoids and assembloids in the lab.

Closed

Applying for Big Ideas Grants

Big Ideas grant applications are currently closed. Stay tuned for announcements about our next call for letters of intent.

Funded Big Ideas projects

Wu Tsai Neurosciences Institute
Big Ideas in Neuroscience Award
2018
Neuro-omics Initiative (Phase 1)

Creating new tools to help neuroscientists bridge the study of genes and proteins operating in the brain to the study of brain circuits and systems, which could lead to a deeper understanding of brain function and disease.

Wu Tsai Neurosciences Institute
Big Ideas in Neuroscience Award
2017
Stanford NeuroTechnology Initiative (Phase 2)

Our goal is to develop the next generation of neural interfaces that match the resolution and performance of the biological circuitry. We will focus on two signature efforts to spearhead the necessary advances: high-density wire bundles for electrical recording and stimulation, and analog and digital bi-directional retinal prostheses for restoration of vision.

Wu Tsai Neurosciences Institute
Big Ideas in Neuroscience Award
2018
Stanford Brain Organogenesis Program (Phase 1)

Developing brain organoids – three dimensional brain tissues grown in the lab – to study human brain development, evolution and neuropsychiatric disorders.

Wu Tsai Neurosciences Institute
Big Ideas in Neuroscience Award
2017
NeuroChoice Initiative (Phase 2)
We propose to connect diverse faculty to deepen interdisciplinary understanding of the neural mechanisms supporting addictive choice by combining conceptual, experimental, and clinical approaches that bridge historically disparate fields of inquiry.
Wu Tsai Neurosciences Institute
Big Ideas in Neuroscience Award
2018
Neurodevelopment Initiative

Investigating how the brain develops from infancy to adulthood across species, focusing on how the interplay between structural development, functional development, experience and affect brain computations and ultimately behavior.

Wu Tsai Neurosciences Institute
Big Ideas in Neuroscience Award
2015
NeuroVision Initiative

The goal is to forge an inter-disciplinary collaboration between physicists, biologists, chemists, and translational medical scientists by inventing new ways of visualizing the brain, from individual molecules to neuronal circuits to entire brain regions, from a normally functioning neuron to a diseased brain.